The makeup designer's job is to make somebody look different than she or he really looks. All designs are based on the requirement that the makeup has to fit an actor. Also taken into account is the time the actor will have to spend having the makeup reapplied every day of the shoot, as opposed to a creature, which can be put on and taken off as easily as a rubber mask. The application can take a long time. To turn Jim Carrey into the Grinch required hours of sitting in a chair every morning before the rest of the crew showed up.
The same type of skills apply to makeup design as to creature design, although most makeup artists will actually sculpt their makeup creations themselves as opposed to having someone else do it. This is a general rule and doesn't hold true for all shops.
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